منابع مشابه
The yin and yang of leishmaniasis control
The relevance of neglected tropical diseases (NTDs) to global poverty and political instability has ignited interest in this group of diseases with the emergence of terms and concepts such as ‘One Health’ and ‘Leaving no one behind’ [1]. Importantly, this led to the materialization of concrete programs and initiatives aiming at control, elimination or even eradication of some NTDs, most notable...
متن کاملThe Yin and Yang of Cell Death Control
Mitochondria are primarily responsible for producing ATP via oxidative phosphorylation in the inner mitochondrial membrane. Because of the high energy demand of the heart, mitochondria comprise at least 30% of the myocyte volume. Mitochondria also play central roles in both necrosis and apoptosis and can quickly change from a source of energy for sustaining contraction to an organelle that prom...
متن کاملThe yin and yang of cyclin control by nutrients
The timing and order of cell cycle progression is regulated by cyclin-dependent kinases (CDKs) to ensure accurate duplication of the genome and other cell components. In budding yeast, accumulation of the cyclin Cln3 (homolog of metazoan Cyclin D) during G 1 activates the major CDK Cdk1 (homolog of CDK4, CDK2 and CDC2). The active Cdk1Cln3 complex induces expression of late G 1 cyclins (homolog...
متن کاملYin yang
oxidative Medicine and celluar Longevity 227 Derived from classical Chinese philosophy and with frequent applications in Chinese medicine, " yin yang " has grown into an interesting concept that may have a number of applications. The term is usually used to depict the existence of polarizing or opposing forces in nature. Yet, the concept of " yin yang " can be much more involved, especially in ...
متن کاملPlatelets: yin and yang.
In this issue of Blood, Boulaftali and colleagues have made the important and novel observation that deficiency of the serine protease inhibitor (serpin), PN-1, in platelets results in a prothrombotic state, supporting the role of platelet PN-1 in thrombosis.1 Specifically, Boulaftali et al have initially confirmed previously published studies by Gronke et al indicating that protease nexin-1 (P...
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ژورنال
عنوان ژورنال: PLOS Neglected Tropical Diseases
سال: 2017
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0005529